CER Groupe FUP

CER Groupe is a Research Center recognized for its integrated expertise serving the diagnostic industry. We support our partners in the development, qualification, and secured supply of proprietary critical raw materials portfolio.

Through advanced platforms combining biotechnology, immunology, bioconjugation and analytics, we help transform ideas into robust, reliable, and compliant diagnostic solutions.

Our strength lies in a comprehensive and agile scientific approach, bridging molecular design, biological production, advanced characterization, and functional validation within a single site.

From antibody and antigen development to conjugation and stabilization process mastery, CER Groupe acts as a strategic partner to strengthen the performance, continuity, and sovereignty of supply chains in the in vitro diagnostics industry.

Critical Raw Materials Development & Production

• Antibody discovery and production
• Antigen design & production (haptens, conjugates, peptides, proteins, cell lines, DNA)
• 12 species for polyclonal antibody large scale production
• Monoclonal antibodies from mouse, rat, rabbit & llama nanobodies
• DNA immunization hybridoma and B cell sequencing technologies
• Antibody engineering (chimerization, antibody fragments)
• Recombinant proteins and antibodies: in E.coli and proprietary high-producing mammalian cells platforms
• Conjugation technologies from stochastic to proprietary regioselective technologies (with enzymes, fluorescents dyes, beads,...)
• Upstream/Dowstream process development and optimization (bioreactor, FPLC, TFF, freeze-drying)
• Native bioproducts extraction: proteins, lipids, tissues, ...

Molecular characterization

• Product characterization: affinity, cross-reactivity, developability, integrity, stability
• Antibody sequencing (VH/VL, full antibody sequencing, de novo sequencing)
• Advanced product quality profiling: N-glycans, N-term variability, impurities, intact mass, peptide mapping
• Conjugate characterization: degree of labelling (DOL) and distribution, residual immuno-reactive fraction (IRF)
• Analytical platforms for customized assays: molecular biology, FACS, immunoassays, cell-based assays, mass spectrometry, molecular interaction

Product/Assay Development

• Assay prototyping: reagent selection, match-pairing studies
• Advanced functionalization strategies (surface, microfluidic, beads...)
• Freeze-drying: process development & routine manufacturing
• Quality control & stability testing
• Validation with human body material samples (biobank certification)
• In vivo imaging systems for medical diagnostic product development

Business Continuity Assurance

• Biomarker portfolio management and back-up supply
• Long-term secured cryostorage & biobanking for human body material (-80°C and gaseous N₂)
• Monoclonal antibody sequencing from hybridoma or purified product